Johnny Depp's teenage daughter has been cast alongside him in a film.

Lily-Rose Depp, the Hollywood's heartthrob's 15-year-old daughter with ex Vanessa Paradis, has bagged a lead role in director Kevin Smith's film Yoga Hosers.

Kevin has also cast his own 15-year-old daughter, Harley Quinn Smith, in the comic book film and she will be playing Lily-Rose's co-lead, according to The Hollywood Reporter's Heat Vision blog.

Both girls previously appeared in Kevin's film Tusks, and Yoga Hosers is a spin off from that.

The action adventure follows two yoga fans played by Lil-Rose and Harley - both named Colleen - who have after school jobs at a shop.

The Hollywood Reporter said of the plot: "When an ancient evil rises from beneath Canada's crust and threatens their big invitation to a Grade 12 party, the Colleens join forces with a legendary man-hunter from Montreal named Guy Lapointe (Johnny) to fight for their lives."

Kevin said: "People always ask me 'Are you ever going to make a comic book movie?' This is it - but instead of yet another dude saving the day, our anti-heroes are the most feared and formidable creatures man has ever encountered: two 15-year-old girls."